Some of those signs were probably made from old, out of date maps, Frontier Fuel was the name of the Ashland Oil Refinery back before the 1960's. The bridge & rail line are part of "The Branch", or the extream North end of the Wonalancet Runner, which is former NYC trackage that origanally serviced the Ashland Oil Refinery to the East of the thruway. The Refinery is closed but the storage tanks and marine unloading dock are maintained in mothball status for any possible future use. The property right next to the Refinery, to the East is now called the Seaway Land Fill, otherwise known as "Mount Tonawanda". There was heavy chemical pollution of the Seaway site with a certain amount of radioactive dirt left over from the WW 2 A-bomb project. The Army Corps was using that line to get loaded waste material cars out of the area for disposal off site. Most of that major work is pretty much done except for the area right around the small creek there. See:
http://www.lrb.usace.army.mil/fusrap/tonsites.htm
-B in B